Melanie Documentation
Find out more with the product brochure, user manual, quick start manual and FAQ.
Software Updates
More information about the latest software release:
The most recent release of Melanie is Version 7.0.6 (5 Apr 2012).
You can check the Release Notes to learn more about the currently available release.
Please register here to download the currently available release.
System Requirements
Melanie 7.0
- Windows® XP, Vista or 7
- Intel® dual-core processor recommended
- Minimum: 500 MB of RAM, recommended: 1 GB of RAM
- Minimum 24-bit color resolution
- Minimum 1024 x 768 screen resolution
- Video card driver needs to support OpenGL® (v1.2 or later)
- Internet Explorer® 6 or Firefox® 3 or higher must be installed to print reports and access databases on the web
Melanie 7.0 DIGE
- Windows® XP, Vista or 7
- Intel® dual-core processor recommended
- Minimum: 768 MB of RAM, recommended: 2 GB of RAM.
- Minimum 24-bit color resolution
- Minimum 1024 x 768 screen resolution
- Video card driver needs to support OpenGL® (v1.2 or later)
- Internet Explorer® 6 or Firefox® 3 or higher must be installed to print reports and access databases on the web
Further Reading
A selection of publications:
Appel RD, Bairoch A, Sanchez J-C, Vargas JR, Golaz O, Pasquali C and Hochstrasser DH (1996) Federated 2-DE database: a simple means of publishing 2-DE data. Electrophoresis 17: 540-546.
Appel RD, Sanchez J-C, Bairoch A, Golaz O, Ravier F, Pasquali C, Hughes GJ and Hochstrasser DF (1996) The SWISS-2DPAGE database of two-dimensional polyacrylamide gel electrophoresis. Nucleic Acids Research 22: 3581-3582.
Binz PA, Mueller M, Walther D, Bienvenut WV, Gras R, Hoogland C, Bouchet G, Gasteiger E, Fabbretti R, Gay S, Palagi P, Wilkins MR, Rouge V, Tonella L, Paesano S, Rossellat G, Karmime A, Bairoch A, Sanchez JC, Appel RD and Hochstrasser DF (1999) A molecular scanner to automate proteomic research and to display proteome images. Analytical Chemistry 71: 4981-4988.
Binz PA, Wilkins MR, Gasteiger E, Bairoch A, Appel RD and Hochstrasser DF (1999) Internet resources for protein identification and characterization. In: Kellner R, Lottspeich F, Meyer HE (eds) Microcharacterization of Proteins, 2nd ed., pp. 277-300. Weinheim: Wiley-VCH.
Cairns, DA (2011) Statistical issues in quality control of proteomic analyses: good experimental design and planning. Proteomics 11:1037-48.
Hoogland C, Baujard V, Sanchez J-C, Hochstrasser DF and Appel RD (1997) Make2ddb: a simple package to set up a 2-DE database on the WWW. Electrophoresis 18: 2755-2758.
Hoogland C, Sanchez J-C, Bairoch A, Hochstrasser DF and Appel RD (1999) The SWISS-2DPAGE database: what has changed during the last year. Nucleic Acids Research 27: 289-291.
Horgan, GW (2007) Sample size and replication in 2D gel electrophoresis studies. Journal of Proteome Research 6:2884-7.
Karp, NA and Lilley, KS (2007) Design and analysis issues in quantitative proteomics studies. Proteomics 7(S1):42-50.
Link AJ (ed) (1998) Methods in molecular biology, Vol 112: 2-D Protocols for Proteome Analysis. Totowa NJ: Humana Press.
Lopez MF (2000) Better approaches to finding the needle in a haystack: optimizing proteome analysis through automation. Electrophoresis 21: 1082-1093.
Sanchez J-C, Wilkins M, Appel RD and Hochstrasser DF (1997) Identifying proteins for proteome studies. In: Creighton ET (ed) Protein Function: a practical approach, 2nd ed., pp. 1-27. IRL Press.
Tonge R, Shaw J, Middleton B, Rowlinson R, Rayner S, Young J, Pognan F, Hawkins E, Currie I and Davison M (2001) Validation and development of fluorescence two-dimensional differential gel electrophoresis proteomics technology. Proteomics 1:377-396.
Unlu M, Morgan ME, and Minden JS (1997) Difference gel electrophoresis: a single gel method for detecting changes in protein extracts. Electrophoresis 18: 2071-2077.
Wilkins MR, Williams KL, Appel RD and Hochstrasser DF (eds) (1997) Proteome research: new frontiers in functional genomics. Berlin Heidelberg: Springer Verlag.
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